Top-Rated Application Control Platforms for Regulated Industries: 8 Solutions Compared

TL;DR: Application control platforms restrict which software can execute on endpoints and servers. Top rated solutions include Airlock Digital (best for default allowlisting at enterprise scale), ThreatLocker (fast approval workflows), Carbon Black App Control (server and fixed-function lockdown), and BeyondTrust EPM (least privilege with application control).

What Is an Application Control Platform and Why Is It Needed for Regulated Industries?

An application control platform is a security solution designed to manage and restrict which applications can run on an organization's endpoints and servers. It operates by enforcing policies that dictate allowed and blocked applications, often using allowlisting (AKA whitelisting), blocklisting (AKA blacklisting), or a combination of both. This approach ensures only trusted and approved software can execute, reducing the risk of unauthorized or malicious applications compromising systems.

Beyond simple allow or deny lists, modern application control platforms offer granular controls over application behavior, file types, and even script execution. They can enforce policies based on user roles, device types, or specific operational requirements. Integration with broader security ecosystems allows these platforms to adapt dynamically to changing threat landscapes and compliance mandates.

Why regulated industries need application control

  • Reducing the attack surface: Limits execution to approved software, blocking unknown apps, malware, scripts, and unauthorized tools before they can run.
  • Protecting critical systems: Helps secure medical devices, financial platforms, industrial systems, kiosks, and legacy assets from unauthorized software changes.
  • Maintaining compliance: Enforces approved software use, supports audit trails, and helps meet requirements such as HIPAA, PCI DSS, SOX, CMMC, and NIST.

In this article:

Application Control Platforms at a Glance

The table below summarizes the key differences between the platforms covered in this guide. We explore each of them in more detail below.

Category Solution Best For Key Strengths User Ratings
Dedicated application control and allowlisting platforms Airlock Digital Deny by Default execution control across Windows, macOS and Linux Granular flexibility with file, path, publisher and parent process trust rules; OTP exceptions 8.6 out of 10 on PeerSpot (12 reviews)
Dedicated application control and allowlisting platforms ThreatLocker Deny by Default allowlisting with fast approval workflows Pre-built application catalog and policy suggestions 4.8 out of 5 on G2 (514 reviews)
Dedicated application control and allowlisting platforms Carbon Black App Control Locking down servers, fixed-function and EOL systems File integrity, device, memory and registry controls 4.6 out of 5 on G2 (45 reviews); 9.2 out of 10 on PeerSpot
Dedicated application control and allowlisting platforms Windows Defender Application Control Kernel-level code integrity enforcement built into Windows at no extra cost Pre-execution enforcement, native OS integration, reputation-based trust via ISG No independent commercial rating published; native OS feature, not a reviewed product
Dedicated application control and allowlisting platforms DriveLock Application Control European-hosted application, device, and encryption control under one console Common Criteria EAL3+ certified control combined with device management and encryption No large-scale aggregate rating on G2 or PeerSpot; individual Capterra/GetApp reviews as high as 9/10
Endpoint and privilege management platforms with application control Trellix Application and Change Control ePO-managed allowlisting for servers and fixed devices Execution control combined with file change control 7.6 out of 10 on PeerSpot (listed as McAfee Application Control)
Endpoint and privilege management platforms with application control Delinea Privilege Manager Pairing endpoint privilege elevation with application control Least-privilege elevation combined with allowlisting, sandboxing, and behavior analytics 4.5 out of 5 on Gartner Peer Insights (76 reviews)

Related content: Read our guide to application control software: key features and top solutions.

Why Regulated Industries Need Application Control

Reducing the Attack Surface

Application control significantly reduces the attack surface by limiting the software that can execute within an organization’s environment. By explicitly allowing only approved applications, organizations eliminate the risk posed by unknown or unauthorized programs, which are common vectors for malware and exploitation. This proactive stance makes it much harder for attackers to introduce malicious code, as even if a system is compromised, the execution of unapproved binaries or scripts is blocked at the outset.

In regulated industries, where endpoints often process sensitive data or control critical infrastructure, minimizing the attack surface is not just a best practice but a necessity. Attackers frequently target these sectors due to the high value of their assets and data. Application control adds a robust security layer, complementing traditional defenses like antivirus and firewalls. By preventing the execution of potentially harmful applications, organizations bolster their resilience against targeted attacks, zero-day threats, and advanced persistent threats (APTs).

Related content: Read our article about ransomware attack types and tell-tale signs.

Protecting Critical Systems

Critical systems in regulated industries—such as medical devices, industrial control systems, or financial transaction platforms—are prime targets for cyberattacks due to their essential role in operations. Application control platforms are essential for safeguarding these assets by preventing the execution of unauthorized or potentially harmful software. Restricting software execution ensures that only validated, tested, and approved applications can interact with critical system components, reducing the risk of disruption or compromise.

In environments where uptime and reliability are paramount, application control also acts as a safeguard against accidental or intentional installation of untested software that could introduce vulnerabilities or destabilize operations. The ability to tightly control what runs on critical systems enables organizations to maintain operational continuity and trust in their most vital infrastructure. This is particularly important for industries where downtime or data breaches can have severe financial, legal, or safety consequences.

Maintaining Compliance

Regulated industries are subject to stringent compliance standards that mandate strict controls over data access, software usage, and system integrity. Application control platforms help organizations enforce these requirements by ensuring that only compliant and vetted software can run on their systems. This control is vital for passing audits and avoiding penalties associated with regulatory violations, such as those imposed by HIPAA, PCI DSS, or SOX.

Moreover, application control provides the auditable records and policy enforcement mechanisms necessary to demonstrate due diligence to regulators. Detailed logs of application activity, policy changes, and exception handling support the documentation required during compliance reviews. By automating the enforcement of software usage policies, organizations reduce the risk of human error and establish consistent, repeatable processes for maintaining regulatory alignment across complex environments.

Application Control Use Cases in Regulated Industries

Application control helps regulated organizations reduce risk by ensuring only approved software, scripts, and system tools can execute. This proactive approach limits malware activity, reduces compliance exposure, and strengthens protection for both modern and legacy environments.

  • Preventing ransomware and malware execution: Blocks unauthorized code from running, stopping ransomware payloads and malware before they can encrypt, exfiltrate, or disrupt regulated operations.
  • Blocking unauthorized software: Prevents unapproved applications from being installed or executed, reducing shadow IT, licensing issues, vulnerabilities, and compliance risks.
  • Controlling scripts and Living off the Land techniques: Restricts scripts, macros, PowerShell, WMI, and similar tools to approved use cases, limiting attacker abuse of legitimate system utilities.
  • Protecting legacy systems: Enforces strict application allowlisting on outdated or unsupported systems, reducing exposure when patching or modernization is not immediately possible.

Essential Features of Application Control Platforms for Regulated Industries

Centralized Policy Management

Centralized policy management allows organizations to define, deploy, and update application control rules from a single interface across all endpoints and servers. This centralized approach streamlines administration, reduces configuration errors, and ensures consistent enforcement of security policies throughout the organization. Security teams can respond quickly to emerging threats or changing compliance requirements by modifying policies in one place and pushing updates enterprise-wide.

In regulated industries, where policy consistency and auditability are critical, centralized management provides the necessary oversight to maintain control. It also simplifies onboarding new systems and scaling the security posture as the organization grows. By centralizing policy management, organizations can better coordinate security efforts and reduce the administrative burden on IT and security staff.

Deny by Default Enforcement

A Deny by Default enforcement model blocks all applications except those explicitly permitted. This approach minimizes the risk of unknown or unauthorized software running in the environment, providing a strong security baseline. Only applications that have been vetted and approved by security or compliance teams are allowed, effectively preventing many types of cyberattacks.

For regulated industries, Deny by Default aligns with best practices for risk management and compliance. It ensures that accidental or intentional installation of risky software is automatically prevented, reducing the chance of non-compliance or security incidents. This enforcement model is fundamental for organizations where the cost of failure is high, such as healthcare, finance, or critical infrastructure sectors.

Comprehensive Execution Control

Comprehensive execution control extends beyond simple application allow or block lists. It includes the ability to manage scripts, installers, libraries, and even specific application behaviors. This granular control ensures that only the right versions and components of applications can execute, further reducing the potential for exploitation or misuse.

Such control is crucial in regulated environments, where unauthorized scripts or outdated libraries can introduce compliance gaps or vulnerabilities. Application control platforms that offer comprehensive execution management help organizations enforce precise software usage policies, maintain system integrity, and support secure development and operational practices.

Flexible Exception Management

While strict controls are necessary, organizations occasionally need to allow exceptions for specific business needs or operational requirements. Flexible exception management enables administrators to grant temporary or conditional access to certain applications, users, or devices without compromising overall security. This flexibility ensures that legitimate work can continue while maintaining a strong security posture.

In regulated industries, exception management must be auditable and governed by policy to avoid introducing unnecessary risk. Application control platforms should provide detailed logging, approval workflows, and expiration mechanisms for exceptions. This ensures that exceptions are managed transparently and do not become long-term vulnerabilities in the environment.

Application Visibility and Intelligence

Application visibility provides insight into all software running across the organization, including version details, usage patterns, and potential risks. Intelligence features enhance this visibility by identifying anomalies, flagging outdated or vulnerable applications, and correlating activity with threat intelligence feeds. This capability enables organizations to maintain an accurate inventory and proactively address risks.

For regulated industries, visibility and intelligence are essential for both security and compliance. They help identify unauthorized software, track policy violations, and support investigations into suspicious activity. Enhanced visibility also aids in demonstrating compliance to auditors and regulators, providing the evidence needed to show that software usage is properly controlled and monitored.

Detailed Audit Logs and Reporting

Application control platforms should record application executions, policy decisions, blocked activity, administrative changes, and exceptions. Logs should include details such as timestamps, users, devices, application identities, and the policy responsible for each action. Centralized reporting makes this data easier to search, correlate, and retain for investigations and compliance reviews.

In regulated environments, detailed records help organizations demonstrate that application control policies are consistently enforced. Reports can provide evidence for audits, identify recurring policy violations, and support incident response by showing what executed before and during a security event. Role-based access and appropriate log retention also help protect audit records from unauthorized modification or deletion.

Top Rated Application Control Platforms for Regulated Industries

How we selected these tools: We shortlisted application control platforms based on Deny by Default enforcement, centralized policy management, script and execution control, exception handling, and the audit logging and reporting that regulated environments depend on.

Dedicated Application Control and Allowlisting Platforms

1. Airlock Digital

Airlock Digital logo

Best for: Deny by Default execution control across Windows, macOS and Linux

Strengths: Granular file, path, publisher and parent process trust rules

Things to consider: Policy upkeep as application versions change

User rating: 8.6 out of 10 on PeerSpot (12 reviews)

Airlock Digital enforces a Deny by Default model in which only trusted applications, scripts and processes are permitted to execute. Trust is defined at the file, path, publisher or parent process level, and policies are created and applied centrally across groups of devices rather than configured machine by machine.

The platform runs on Windows, macOS and Linux, including legacy operating systems, and supports on-premises, cloud and offline or air-gapped environments. Enforcement can be introduced gradually, moving from audit visibility toward full Deny by Default, and it connects to EDR, SIEM, identity and IT service workflows, and is used to satisfy NIST, CMMC, PCI DSS, and Essential Eight requirements.

Key features include:

  • Granular policy control: Trusted applications are defined at the file, path, publisher or parent process level, with role-based governance over who can change policy.
  • Exception management and one-time passwords: Rule-based overrides handle specific scenarios, and a secure OTP mechanism allows temporary execution of untrusted applications for a defined period.
  • Trust Builder: Analyzes execution activity within a policy group and generates publisher, path, parent process and grandparent process rule recommendations. Administrators can review, approve, suppress or auto-apply qualifying rules within configured thresholds, and guardrails suppress candidates in temporary paths, user-writable locations and shell processes.
  • Trusted Installer: Natively supported on Windows, including complex deployment chains. Allows software deployed through SCCM/MECM, Intune, Jamf and BigFix to execute, tags application components during installation, and adds installed applications and their dependencies to the allowlist while logging all installer activity.
  • Elevation Control: Applies administrative-equivalent privileges to approved applications and processes through allowlist metadata rules, with publisher, path, parent process and user context conditions, across Windows, Linux and macOS including command-line workflows.
  • Application Context: Groups related files and libraries into recognizable applications based on how they execute together, surfaces categories such as remote access, VPN/VDI and AI tools, and distinguishes historically observed software from actively running software.
  • Browser extension control: Approved extensions are allowlisted by properties including extension ID across Chrome, Edge and Firefox, with unapproved or modified extensions blocked and usage reported centrally.
  • File-level intelligence and audit records: VirusTotal reputation data informs allowlisting decisions, and policy change history records how policy was created and by whom.

Limitations (as reported by users on PeerSpot):

  • Documentation depth: Administrators new to the platform reported the initial learning period was confusing and asked for a more detailed user manual and more implementation examples.
  • Reporting customization: Reviewers would like more customizable dashboards and easier ways to generate compliance and operational reports for different audiences.
  • Agent release cadence: Organizations working under strict change management noted that new agent versions arrive every few months, which takes effort to keep pace with.

Airlock Digital screenshot

Source: Airlock Digital

2. ThreatLocker

ThreatLocker logo

Best for: Deny by Default allowlisting with fast approval workflows

Strengths: Pre-built application catalog and suggested policies

Things to consider: Policy tuning and approval volume need ongoing time

User rating: 4.8 out of 5 on G2 (514 reviews)

ThreatLocker allowlisting blocks any application, script or library that has not been approved. Once the agent is deployed it catalogs applications and dependencies, drawing on more than 15,000 recognized applications, and produces policy suggestions rather than requiring administrators to build lists from scratch.

Approvals are made in one click. Users request access to new applications through a popup, and requests are handled either internally or by ThreatLocker's Cyber Hero team, which responds in about 60 seconds. Deny by Default execution is used to satisfy NIST, CMMC, CIS and Essential Eight requirements.

Key features include:

  • Deny by Default execution: Only approved applications, scripts and libraries execute; everything else is blocked, including ransomware payloads.
  • Application cataloging and policy suggestions: The agent automatically inventories applications and dependencies against a library of over 15,000 pre-built applications and proposes policies on the fly.
  • Approval workflows: End users raise requests through a popup, administrators approve internally, or the Cyber Hero team handles approvals; an application store provides trusted applications and alternatives for users to deploy.
  • Policy expirations: Permissions can be time-bound, so a tool such as a network scanner can be permitted only during a defined window and blocked at all other times.
  • Execution visibility: Every application, dependency and update in the environment is visible, with control over what runs, when, where and by whom.
  • Community execution data: For unknown applications, administrators can see how often the application runs, how many environments it appears in, whether other administrators allowed or blocked it, plus threat history and reputation trends, and generate suggested policies from that data.
  • Shadow IT control: Rogue installs, unsanctioned tools and hidden software are blocked across the network.

Limitations (as reported by users on G2):

  • Learning curve: The most frequently raised issue is the effort required to learn the policy model, particularly for teams without dedicated security staff.
  • Configuration complexity: Reviewers describe configuration and troubleshooting as challenging, often needing vendor assistance to work out why something was blocked.
  • Update and approval overhead: Application updates and changed DLLs can be blocked until reviewed, which generates administrative work in environments where software changes frequently.
  • macOS parity: Some users report compatibility gaps in the macOS version compared with Windows.
  • Reporting: Reviewers describe reports as noisy or incomplete and would like output that can be tailored for different audiences.
  • Older hardware: Devices with limited system resources were reported to run more slowly with the agent installed.

ThreatLocker screenshot

Source: ThreatLocker

3. Carbon Black App Control

Carbon Black App Control logo

Best for: Locking down servers, fixed-function and end-of-life systems

Strengths: File integrity, device, memory and registry controls in one agent

Things to consider: List upkeep and false positives in large estates

User rating: 4.6 out of 5 on G2 (45 reviews); 9.2 out of 10 on PeerSpot

Carbon Black App Control applies a positive security model to servers and critical systems, allowing only software with a verified level of trust to execute. Unknown software is untrusted by default and must be explicitly vetted before it can run, which prevents unauthorized changes to system configurations.

Deployment covers on-premises data centers, AWS, Microsoft Azure and hosted private clouds. It is used on air-gapped systems, fixed-function devices such as ATMs, point-of-sale terminals, kiosks and medical machinery, and end-of-life operating systems including Windows XP, Windows Server 2003 and Windows Server 2008.

Key features include:

  • Application control: Allowlisting and denylisting enforce granular rules on how applications execute and interact with system resources.
  • File integrity monitoring and control: Tracks alterations to sensitive files, registry keys and host operating system folders. Monitoring alerts on unauthorized changes, while file integrity control blocks them.
  • Device control: Regulates data transfers to and from external media such as USB drives, with access rules that permit or restrict connections by user, group or schedule.
  • Memory and registry protection: Enforces memory access boundaries so processes cannot read from or inject code into unauthorized memory space, and locks system-critical Windows registry keys against tampering.
  • Trusted content approval: Avoids manual hash list maintenance by combining pre-approved trusted directories, cloud reputation scores, trusted publishers such as Microsoft, Google and Adobe, and custom rules based on path, process, user or publisher.
  • External analysis integrations: Unknown files are routed automatically for static or dynamic analysis and then approved or banned by event rules based on the result.
  • Inventory and platform coverage: Application catalog inventory and Common Platform Enumeration identify all software running in critical environments, with sensors for Windows including Embedded and POS and ARM64, macOS, Red Hat Enterprise Linux and Oracle Linux.

Limitations (as reported by users on PeerSpot):

  • List maintenance overhead: Reviewers note the ongoing effort involved in keeping lists of permitted and blocked applications current.
  • False positives: Users report blocks against operating system components, store applications and newly introduced processes, particularly in the early stages of a deployment.
  • Publisher rule reliability: Even when a publisher is approved, certificate validation issues have occasionally stopped legitimate processes from running in large environments.
  • Scalability: Some reviewers rate scalability noticeably lower than stability, citing effort required as the estate grows.

Carbon Black App Control screenshot

Source: Carbon Black

4. Windows Defender Application Control

Windows Defender Application Control logo

Best for: Kernel-level code integrity enforcement built into Windows at no extra cost

Strengths: Pre-execution enforcement, native OS integration, reputation-based trust via ISG

Things to consider: Policy authoring complexity and no dedicated vendor support channel

User rating: No independent commercial rating is published on G2 or PeerSpot; WDAC is a built-in Windows platform capability rather than a separately purchased and reviewed product.

Windows Defender Application Control is a code integrity feature built into Windows 10, Windows 11, and Windows Server 2016 and later, rather than a separately licensed product. It enforces a Deny by Default model at the kernel level, evaluating every executable, script, driver, and DLL against an administrator-defined policy before it is allowed to load into memory. Because enforcement happens before code execution rather than at the process level, Microsoft and independent security researchers generally regard WDAC as harder to bypass than its predecessor, AppLocker, which it is intended to supersede in modern environments.

Policies are built and deployed through Group Policy, Microsoft Intune, or the WDAC Wizard tool, and organizations typically start in audit mode to capture a baseline of legitimate software before switching to enforcement. WDAC integrates with the broader Microsoft security stack, including Microsoft Defender for Endpoint, Credential Guard, and BitLocker, and can enforce Constrained Language Mode for PowerShell to close off common Living off the Land attack paths.

Key features include:

  • Kernel-level code integrity enforcement: Validates executables, scripts, MSIs, and drivers before they load into memory, rather than after a process has already started.
  • Policy templates for common trust levels: Ships with templates such as Default Windows Mode, Allow Microsoft Mode, and Signed Reputable Mode, the last of which integrates Microsoft's Intelligent Security Graph to score application reputation.
  • Managed Installer support: Designates trusted deployment tools such as Microsoft Intune, SCCM/MECM, or other managed installers, automatically trusting software they deploy without manual allowlisting.
  • PowerShell Constrained Language Mode: Restricts PowerShell to a safer subset of language features when WDAC is enforced, blocking common script-based attack techniques.
  • Signed driver enforcement: Requires drivers to be signed by Windows Hardware Quality Labs partners holding an Extended Verification certificate, reducing the risk of malicious or vulnerable drivers loading at the kernel level.
  • Audit-first deployment workflow: Policies can run in audit mode, logging what would have been blocked to Windows Event Viewer, so administrators can validate a policy against real-world usage before enforcing it.
  • Centralized management at scale: Deployable and monitorable through Group Policy, Intune, and Windows Admin Center for enforced infrastructure, including servers and clusters.

Limitations (based on publicly available sources):

  • Authoring complexity: Building, testing, and merging WDAC policies (base and supplemental policies, path rules, publisher rules) requires more upfront investment and expertise than simpler allowlisting tools, and is commonly cited as the biggest barrier to adoption.
  • No dedicated vendor support: As a built-in OS feature rather than a purchased product, organizations troubleshoot through Microsoft's general documentation and community resources rather than a dedicated account team or support SLA.
  • Deployment risk without staging: A WDAC policy that blocks too aggressively can break legitimate applications, which is why Microsoft's own guidance recommends a mandatory 1–2 week audit period before enforcement.
  • Console fragmentation: Managing WDAC-enforced infrastructure at scale typically spans Group Policy, Intune, and Windows Admin Center, rather than a single unified console purpose-built for the feature.
  • No independent review benchmarking: Because WDAC isn't sold or reviewed as a standalone product, there's no G2 or PeerSpot rating to benchmark it against dedicated commercial application control platforms.

Windows Defender Application Control screenshot

Source: Windows

5. DriveLock Application Control

DriveLock Application Control logo

Best for: European-hosted application, device, and encryption control under one console

Strengths: Common Criteria EAL3+ certified control combined with device management and encryption

Things to consider: Workflow still split across two consoles; limited aggregate review volume

User rating: No large-scale aggregate rating is currently published on G2 or PeerSpot; individual Capterra and GetApp reviews are strongly positive, with reviewers scoring the product as high as 9 out of 10.

DriveLock is a German-headquartered endpoint security vendor whose HYPERSECURE platform combines application control, device control, encryption, and vulnerability management under one umbrella, positioned for regulated sectors including government, healthcare, finance, and manufacturing. Application Control blocks all applications, scripts, and DLLs that are not explicitly on an organization's allowlist, and pairs that enforcement with Application Behavior Control, which governs how already-approved applications are permitted to interact with the system once running.

The platform is offered as both a cloud-based and on-premises deployment, giving European organizations with data residency requirements a choice of hosting model. DriveLock's application and device control capabilities are certified to Common Criteria EAL3+, and the company states its broader platform is built to support compliance with standards including BSI, C5, GDPR, NIS2, TISAX, and ISO 27001.

Key features include:

  • Deny by Default application control: Blocks any application, script, or DLL not present on the organization's whitelist, backed by intelligent, automated allowlisting to reduce manual list maintenance.
  • Application Behavior Control: Defines how approved applications are permitted to interact with the system after launch, adding a layer of control beyond simple execution decisions.
  • Common Criteria EAL3+ certification: Application and device control capabilities carry this certification, giving regulated buyers an independently assessed security baseline.
  • Combined device and application control: Manages USB and removable media access alongside application execution from the same policy engine, addressing both vectors in one console.
  • Central dashboards and customized notifications: Provides centralized evaluation dashboards and configurable end-user notifications when an application or device is blocked.
  • Encryption and vulnerability management add-ons: Extends beyond application control into full-disk and container encryption, plus vulnerability and patch management, from the same underlying platform.
  • Flexible hosting model: Available as a cloud-based solution hosted on Microsoft Azure or as an on-premises install, supporting organizations with strict data residency needs.

Limitations (as reported by users on Capterra and GetApp):

  • Split console workflow: Reviewers note they still need to move between two separate consoles to complete some tasks, and are waiting for full functionality to consolidate into the web console.
  • Drive cleanup gaps: One reviewer notes there is no way to automatically delete released drives that haven't been used for a defined number of days, requiring manual housekeeping.
  • Event loading performance: Some reviewers mention that event data doesn't always load promptly from the DOC (DriveLock Operations Center) component.
  • Limited English-language review volume: Much of the available user feedback is in German and concentrated on smaller review platforms, giving prospective buyers less independent English-language benchmarking than larger competitors receive on G2 or PeerSpot.
  • No aggregate star rating on major platforms: As of this writing, DriveLock does not have a substantial review base on G2 or PeerSpot specifically for its Application Control product, limiting side-by-side benchmarking against category leaders.

DriveLock Application Control screenshot

Source: DriveLock

Endpoint and Privilege Management Platforms with Application Control

6. Trellix Application and Change Control

Trellix Application and Change Control logo

Best for: ePO-managed allowlisting for servers and fixed-function devices

Strengths: Execution control combined with file change control

Things to consider: Reporting and policy configuration need attention

User rating: 7.6 out of 10 on PeerSpot, listed under the product's former name, McAfee Application Control

Trellix Application and Change Control restricts execution to trusted applications on desktops, servers and fixed-function devices. Application Control handles the allowlisting side, while Change Control write-protects and read-protects critical files against unauthorized tampering.

Rules can combine file name, process name, parent process name, command line parameters and username. Trellix Global Threat Intelligence supplies file, message and sender reputation data drawn from sensors worldwide, and the product is managed through Trellix ePolicy Orchestrator alongside the wider Trellix endpoint stack.

Key features include:

  • Advanced execution control: Rules combine file name, process name, parent process name, command line parameters and username, so execution decisions account for how a process was launched.
  • Change control: Critical files can be write-protected and read-protected against unauthorized tampering, alongside application execution restrictions.
  • Dynamic policy discovery: Policies adapt to changing desktop environments so an allowlisting strategy can be applied without a rigid lockdown.
  • Inventory search and pre-defined reports: Built-in search and reporting locate vulnerabilities, compliance gaps and security issues across the managed estate.
  • Global Threat Intelligence: File, message and sender reputation is tracked in real time using millions of sensors and applied to execution decisions.
  • User notifications and self-approvals: End users can install new applications through notification and self-approval workflows rather than raising a ticket for every request.
  • Centralized management: Policy is administered through Trellix ePolicy Orchestrator, the same console used for Trellix Endpoint Security and EDR.

Limitations (as reported by users on PeerSpot):

  • Reporting and alerting: Reviewers repeatedly ask for better reporting and alerting in future versions.
  • Policy configuration: Users report problems with parent and child process relationships in policy configuration on certain versions.
  • Policy creation effort: Reviewers would like an easier configuration path, including more monitoring of operating modes so administrators can see what is running before writing rules.
  • Deployment expertise: The product is described as requiring a structured deployment process and technical expertise for optimal setup.

Trellix Application and Change Control screenshot

Source: Trellix

7. Delinea Privilege Manager

Delinea Privilege Manager logo

Best for: Pairing endpoint privilege elevation with policy-based application control

Strengths: Least-privilege elevation combined with allowlisting, sandboxing, and behavior analytics

Things to consider: Setup and policy tuning take time; reporting customization has room to grow

User rating: 4.5 out of 5 on Gartner Peer Insights (76 reviews)

Delinea Privilege Manager (formerly Thycotic Privilege Manager) combines endpoint privilege elevation with application control, aimed at removing standing local administrator rights while still letting approved applications run with the permissions they need. Rather than granting a user broad admin access, Privilege Manager elevates specific applications on a policy basis, so a user can run a trusted tool that requires elevated rights without holding admin privileges more broadly across the endpoint.

The product discovers Windows and Mac accounts and applications across the endpoint estate, then applies application control features including sandboxing, UAC override, child process control, and real-time application analysis on top of the elevation model. It is available as both a cloud-based and on-premises deployment, with the cloud version built to scale across hundreds of thousands of machines, and it integrates with Delinea's own Secret Server and Privileged Behavior Analytics as well as third-party SIEM, ticketing, and identity systems.

Key features include:

  • Least-privilege elevation: Removes standing local administrative rights from endpoints and elevates specific applications rather than entire user sessions, reducing the blast radius available to malware.
  • Granular application control policies: Combines blocking, elevation, monitoring, and justification policies with flexible deployment configurations to match different user and machine groups.
  • Application discovery: Automatically discovers Windows and Mac accounts and applications running with administrative or root privileges across the endpoint estate.
  • Just-in-time access and approval workflows: Supports end-user justification prompts and admin approval workflows so users can request elevated access to specific applications without a standing grant.
  • Application control depth: Includes sandboxing, UAC override handling, child process control, and real-time application analysis to govern how elevated applications behave once running.
  • Centralized logging and reporting: Provides centralized application and execution event logging, local user and group activity auditing, and customizable dashboards covering application usage, blocked malware, and least-privilege compliance.
  • Ecosystem integrations: Connects natively with Active Directory, Entra ID, ServiceNow, ConfigMgr (SCCM), VirusTotal, SIEM platforms, and Delinea's own Secret Server and Privileged Behavior Analytics for enriched monitoring.

Limitations (as reported by users on Gartner Peer Insights):

  • Setup and configuration effort: Some reviewers describe the initial deployment and policy configuration process as requiring meaningful time investment before the platform runs smoothly in production.
  • Policy tuning overhead: Because elevation and application control policies must be tailored per application and user group, ongoing tuning is needed as the software estate changes.
  • Reporting and dashboard customization: Reviewers note that while reporting covers the essentials, more flexible or tailored dashboard views would help different stakeholders (executives versus IT administrators) get the specific data they need.
  • Learning curve for granular controls: Administrators new to the least-privilege elevation model, as opposed to traditional allowlisting alone, describe a learning period before the granular policy options (sandboxing, UAC override, child process control) feel intuitive to configure.

Delinea Privilege Manager screenshot

Source: Delinea

Conclusion

Selecting the right platform requires evaluating how well each solution aligns with your industry-specific compliance standards and technical environment. Prioritize systems that offer robust visibility, scalable policy management, and the flexibility to secure both modern endpoints and legacy assets. A balanced approach ensures strong security without disrupting critical operations, effectively reducing risk while meeting stringent regulatory demands.